1. 毕业设计（论文）的内容和要求
本课题将设计构建以嵌段共聚物聚氧乙烯-聚氧丙烯-聚氧乙烯(PEO-PPO-PEO)、透明质酸和小分子交联剂(3,3'-二硫代双(丙酰肼))为原料，基于Pluronics F127水溶液体系的胶束化和凝胶化作用以及动态共价键酰腙键作用，并具有氧化还原、pH和温度多重响应性能的水凝胶材料。
通过对PluronicsF127进行醛基功能化修饰，对透明质酸的氧化，为其与小分子交联剂进行动态共价键交联提供了位点；通过PluronicsF127水溶液体系的胶束化，为水凝胶体系提供规整的疏水区，也将醛基位点曝露于胶束的外部；结合动态共价键交联、胶束化作用和疏水作用，酰腙键的形成，以及含二硫键小分子交联剂的引入，同时赋予了水凝胶氧化还原、pH和温度响应的特性，实现了水凝胶的温和成胶和多重响应性构筑的双重目标。
在设计构建具有多重响应性水凝胶的基础上，一步研究氧化还原、pH和温度响应性能的影响因素和控制规律。
2. 参考文献
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