1. 毕业设计（论文）的内容和要求
针对呋喃二甲酸正辛醇酯的酶法合成，建立反应底物和产物的分析测试方法，构建并优化脂肪酶催化合成呋喃二甲酸正辛醇酯的反应体系，探索反应条件、溶剂和酶对转酯化收率的影响规律。
2. 参考文献
[1] 石志博, 姚宁, 朱玉等. 邻苯二甲酸酯类增塑剂的正确评价和使用[J]. 塑料助剂, 2009(5): 43-49.[2] MATTHEWS G. PVC: production, properties and uses. London, England: Institute of Metals[M]. The Institute of Materials, Printed and Bound in Great Britain at the University Press, Cambridge, 1996. [3] 张颖, 陈浩乾. 增塑剂的研究与发展[J]. 广州化工, 2009, 37(4): 49-51.[48] ROSEN S L. Fundamental principles of polymeric materials,2nd edition[M]. New York: Wiley, 1993. [4] YANF L, MILUTINOVIC P S, et al. The plasticizer di(2-ethylhexyl) phthalatemodulates gamma-aminobutyric acid type A and glycine receptor function[J].Anesth Analg, 2007, 105(2): 393-396.[5] WINGBORG N, ELDSATAR.2,2-Dinitro-1,3-Bis-Nitrooxy-Propane(NPN): A New Energetic Plasticizer[J]. Propellants Explosives Pyrotechnics, 2002, 27(6): 314-319.[6] SOTHOMVIT R, KROCHTA J M. Plasticizer effect on mechanical propertiesof β-lactoglobulin films[J]. Journal of Food Engineering, 2001, 50: 149-155. [7] PARK H M, MISRA M, DRZAL L T. Green Nanocomposites fromcellulose acetate bioplastic and Clay: Effect of eco-friendly triethyl citrate plasticizer[J]. Biomacromolecules, 2004, 5(6): 2281-2288. [8] NIHUL P G, MHASKE S T, SHERTUKDE V V. Epoxidized rice bran oil (ERBO) as a plasticizer for poly(vinyl chloride) (PVC) [J]. Iranian Polymer Journal, 2014, 23(8): 599-608. [9] 刘彦坤, 王小萍, 罗远芳. 聚氯乙烯环保型增塑剂的研究进展[J]. 化工进展, 2008, 27(1): 74-77. [10] 王波, 王克智, 巩翼龙. 环保型增塑剂的研究进展[J]. 塑料工业, 2013, 41(5): 12-15. [11] 蒋平平, 张书源, 冷炎. 催化合成环保增塑剂的研究及其应用进展[J]. 化工进展, 2012, 31(5): 953-964.[12] 林国良, 陈登龙, 黄宝铨. 邻苯二甲酸酯类增塑剂替代品的研究进展[J].塑料助剂, 2007, 65(5): 1-4.[13] BETIGERI S S, NEAU S H. Immobilization of lipase using hydrophilic polymers in the form of hydrogel beads[J]. Biomaterials, 2002, 23(17): 3627.[14] CHEN R Q. Development of phthalate and environmental friendly plasticizer substitute[J]. Textile Auxiliaries, 2011.[15] 刘仁清. 国内外增塑剂工业发展概况[J]. 聚氯乙烯，1985(6):53-56.[16] MANN B M, BUCHANAN S W. Pacemaker having PVC response and PMT terminating features: US, US 4788980 A[P]. 1988.
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