荧光淬灭法测定HbA1c装置设计与制作任务书

 2021-11-05 19:05:27

1. 毕业设计(论文)的内容和要求

糖尿病是一组以高血糖为特征的代谢性疾病。

高血糖则是由于胰岛素分泌缺陷或其生物作用受损,或两者兼有引起。

糖尿病时长期存在的高血糖,导致各种组织,特别是眼、肾、心脏、血管、神经的慢性损害、功能障碍。

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2. 参考文献

[1] Blincko S , Edwards R . Quenching of Fluorescence by Glycated Haemoglobin: Early Development of a Novel Assay[J]. Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine, 1998, 35(1):140-142.[2] Blincko S , Edwards R . Non-separation assay for glycohemoglobin[J]. Clinical Chemistry, 1998, 44(6 Pt 1):1302-1308.[3] Blincko S , Colbert D A , John W G , et al. A reliable non-separation fluorescence quenching assay for total glycated serum protein: a simple alternative to nitroblue tetrazolium reduction[J]. Annals of Clinical Biochemistry, 2000, 37(3):372-379.[4] Blincko S , Anzetse J , Edwards R . Measurement of Glycated Haemoglobin in whole Blood by a Novel Fluorescence Quenching Assay[J]. Annals of Clinical Biochemistry: An international journal of biochemistry and laboratory medicine, 2000, 37(4):492-497.[5] Edwards R, Blincko S. Glycated proteins assay.International Patent Application PCT/GB95/01766; US Patent 08/765,461[6] S Blincko, R Edwards. Current issues in glycated haemoglobin measurement[J]. Clinical Laboratory, 2001, 47(7-8):377-385.[7] Oshiro I , Takenaka T , Maeda J . New method for hemoglobin determination by using sodium lauryl sulfate (SLS)[J]. Clinical Biochemistry, 1982, 15(2):83-88.[8] Zander R , Lang W , Wolf H U . Alkaline haematin D-575, a new tool for the determination of haemoglobin as an alternative to the cyanhaemiglobin method. I. Description of the method.[J]. Clinica Chimica Acta, 1984, 136(1):83-93.[9] Moharram N M M , Aouad R E , Busaidy S A , et al. International collaborative assessment study of the AHD method for the measurement of blood haemoglobin[J]. Eastern Mediterranean health journal = La revue de sant de la Mditerrane orientale = al-Majallah al-iīyah li-sharq al-mutawassi, 2006, 12(6):722-734.[10] 涂文瑞,卢爱薇. 碱性羟基高铁血红素(AHD-575)法测定血红蛋白的探讨[J]. 学会(10):39-40.

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