1. 毕业设计(论文)的内容和要求
Si3N4陶瓷具有生物活性、优异的抗菌性、较高的韧性、高强度、高硬度、耐腐蚀、抗氧化及机械冲击性能,密实氮化硅材料的理论抗弯强度可达到1000~1500MPa、抗压强度3500MPa,且其密度较低,仅为1.8~3.2g/cm3。
一般来说,材料的孔隙度越高,其强度越差,而基于密实氮化硅材料的优异性能,理论上经过适当的成孔技术,可以使得其密度、强度以及韧性同时达到与人骨相当的性能。
因此本课题采用发泡凝胶工艺制备氮化硅多孔陶瓷坯体,通过研究主要工艺参数对陶瓷体孔隙结构和力学、生物性能的影响,掌握最佳工艺参数。
2. 参考文献
根据毕业要求指点2.3,毕设期间要进行研究现状调查与总结,要求在开题报告及毕业设计(论文)中涉及的参考文献不少于20篇,其中近5年不少于8篇,英文文献不少于5篇。
以下是与本课题相关的部分文献列表:(学生在此基础上,自行查阅补充)[1] 倪卓, 杨莎, 王应, et al. 骨替代材料的研究方法及进展 [J]. 深圳大学学报(理工版), 2015, 32(4): 331-42.[2] BOCK R M, MCENTIRE B J, BAL B S, et al. Surface modulation of silicon nitride ceramics for orthopaedic applications [J]. Acta biomaterialia, 2015, 26(318-30.[3] ZHANG R, MA P X. Porous poly(L‐lactic acid)/apatite composites created by biomimetic process [J]. Journal of Biomedical Materials Research, 2015, 45(4): 285-93.[4] 何春耒, 王大平, 马经野. 骨组织工程支架材料的种类及发展趋势 [J]. 中国组织工程研究, 2009, 13(25): 4905-8.[5] PEZZOTTI G, MCENTIRE B J, BOCK R, et al. Silicon Nitride: A Synthetic Mineral for Vertebrate Biology [J]. Scientific reports, 2016, 6(31717.[6] PEZZOTTI G, MARIN E, ADACHI T, et al. Bioactive silicon nitride: A new therapeutic material for osteoarthropathy [J]. Scientific reports, 2017, 7(44848.[7] BAL B S, RAHAMAN M N. Orthopedic applications of silicon nitride ceramics [J]. Acta biomaterialia, 2012, 8(8): 2889-98.[8] FRAJKOROVF, BODIOVK, BOH M, et al. Preparation and characterisation of porous composite biomaterials based on silicon nitride and bioglass [J]. Ceramics International, 2015, 41(8): 9770-8.[9] BODIOVK, KAIAROVM, DOMANICKM, et al. Porous silicon nitride ceramics designed for bone substitute applications [J]. Ceramics International, 2013, 39(7): 8355-62.[10] YIN L, ZHOU X, YU J, et al. Preparation of silicon nitride foam with three-dimensional interconnected pore structure [J]. Materials Design, 2016, 89(620-5.[11] MIN L, JIA C, JING M, et al. Biomimetic Synthesis of Porous Si3N4 Ceramics仿生制备多孔氮化硅陶瓷 [J]. 无机材料学报, 2008, 23(4): 763-8.[12] XU C, BAI Y, YANG S, et al. A versatile three-dimensional foam fabrication strategy for soft and hard tissue engineering [J]. Biomedical Materials, 2018, 13(2): 025018.[13] BODIOVK, KAIAROVM, VILCEKOVA Z, et al. Mechanical properties of macroporous silicon nitride-based ceramics designed for bone substitutes [J]. Ceramics Silikaty, 2014, 58(2): 99-105.[14] CHEN M, WANG C, WANG H, et al. Fabrication of hierarchically porous Si3N4 foam ceramics with stamen-like cell structure [J]. Materials Letters, 2014, 132(10): 119-22.[15] ODUWOLE K O, MOLONY D C, WALLS R J, et al. Increasing financial burden of revision total knee arthroplasty [J]. Knee Surgery Sports Traumatology Arthroscopy, 2010, 18(7): 945-8.
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