1. 毕业设计（论文）的内容和要求
本课题将依据查找到的文献利用还原法和晶种生长法制备具有不同外形，不同表面修饰以及不同粒径的金纳米粒子，并对其光谱吸收的特性进行研究表征。
采用控制变量法分别研究粒径、形状及表面修饰对金纳米粒子近红外光热效应的影响。
在分别了解各个因素与金纳米粒子的近红外光热效应相关性的基础上，探究它们的协同作用，并制备一种近红外光热效应强的金纳米粒子，使其LSPR峰宽化且发生明显红移，到达近红外区。
2. 参考文献
根据毕业要求指点10.2，毕设期间要进行研究现状调查与总结，要求在开题报告及毕业设计（论文）中涉及的英文文献不少于20篇，其中近5年不少于8篇，英文文献不少于5篇。
以下是与本课题相关的部分文献列表： [1]Bianco, A., Kostarelos, K., 679. https://doi.org/10.1016/j.cbpa.2005.10.005[2]Chen, R. J., Zhang, Y., Wang, D., 3839. https://doi.org/10.1021/ja010172b[3]Chen, Robert J., Bangsaruntip, S., Drouvalakis, K. A., Wong Shi Kam, N., Shim, M., Li, Y., Dai, H. (2003). Noncovalent functionalization of carbon nanotubes for highly specific electronic biosensors. Proceedings of the National Academy of Sciences of the United States of America, 100(9), 49844989. https://doi.org/10.1073/pnas.0837064100[4]Eatemadi, A., Daraee, H., Karimkhanloo, H., Kouhi, M., Zarghami, N., Akbarzadeh, A., Joo, S. W. (2014). Carbon nanotubes: Properties, synthesis, purification, and medical applications. Nanoscale Research Letters, 9(1), 113. https://doi.org/10.1186/1556-276X-9-393[5]Gu, W., Zhang, J., Peng, L., Cao, W., Deng, H., Tao, W. (2018). Photothermal characteristics of gold nanoparticles of different size, shape, and composition: application in photothermal therapy. Hongwai Yu Jiguang Gongcheng/Infrared and Laser Engineering, 47(11), 19. https://doi.org/10.3788/IRLA201847.1121005[6]Huang, X., El-Sayed, M. A. (2010). Gold nanoparticles: Optical properties and implementations in cancer diagnosis and photothermal therapy. Journal of Advanced Research, 1(1), 1328. https://doi.org/10.1016/j.jare.2010.02.002[7]Kam, N. W. S., Dai, H. (2005). Carbon nanotubes as intracellular protein transporters: Generality and biological functionality. Journal of the American Chemical Society, 127(16), 60216026. https://doi.org/10.1021/ja050062v[8]Kam, N. W. S., Jessop, T. C., Wender, P. A., Dai, H. (2004). Nanotube molecular transporters: Internalization of carbon nanotube-protein conjugates into mammalian cells. Journal of the American Chemical Society, 126(22), 68506851. https://doi.org/10.1021/ja0486059[9]Lim, D. K., Barhoumi, A., Wylie, R. G., Reznor, G., Langer, R. S., Kohane, D. S. (2013). Enhanced photothermal effect of plasmonic nanoparticles coated with reduced graphene oxide. Nano Letters, 13(9), 40754079. https://doi.org/10.1021/nl4014315[10]Liu, J., Chang, M. J., Gao, B., Xu, Z. G., Zhang, H. L. (2013). Sonication-assisted synthesis of multi-functional gold nanorod/silica core-shell nanostructures. Journal of Alloys and Compounds, 551, 405409. https://doi.org/10.1016/j.jallcom.2012.11.042[11]Liu, Z., Tabakman, S., Welsher, K., Dai, H. (2009). Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery. Nano Research, 2(2), 85120. https://doi.org/10.1007/s12274-009-9009-8[12]Werner, D., Hashimoto, S., Uwada, T. (2010). Remarkable photothermal effect of interband excitation on nanosecond laser-induced reshaping and size reduction of pseudospherical gold nanoparticles in aqueous solution. Langmuir, 26(12), 99569963. https://doi.org/10.1021/la100015t[13]Ye, E., Win, K. Y., Tan, H. R., Lin, M., Teng, C. P., Mlayah, A., Han, M. Y. (2011). Plasmonic gold nanocrosses with multidirectional excitation and strong photothermal effect. Journal of the American Chemical Society, 133(22), 85068509. https://doi.org/10.1021/ja202832r[10] 杨页如. 无机非金属材料测试方法[M]. 武汉: 武汉理工大学大学出版社, 1990.[11] 高聚物合成工艺学/赵进修订;赵德仁,张慰盛编，第3版-北京:化学工业出版社,2013.5 [12] 无机及分析化学/冯辉霞,杨万明主编.―2版.一武汉:华中科技大学出版社,2018.7
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