1. 毕业设计（论文）的内容和要求
本论文的主要内容是对磁性Fe3O4/SiO2气凝胶载阿霉素造影剂国内外的研究现状、应用与发展进行了简要的阐述。
简述磁性Fe3O4/SiO2气凝胶载阿霉素造影剂的结构特点、制备工艺和医学应用前景。
通过将磁性Fe3O4磁性材料均匀分散在溶胶中，经过凝胶、老化、超临界干燥工艺后制得磁性Fe3O4/SiO2气凝胶，在此基础上将磁性气凝胶与阿霉素等进行复合制备出造影剂。
2. 参考文献
根据毕业要求指标点10.3，毕业论文期间要进行研究现状调查与总结，要求在开题报告及毕业论文中涉及的英文文献不少于20篇，其中近5年不少于8篇，英文文献不少于5篇。
以下是与本课题相关的部分文献列表：[1] Iswar S , Malfait W J , Balog S , et al. Effect of aging on silica aerogel properties[J]. Microporous synthesis, properties and characterization[J]. Journal of Materials Processing Tech, 2008, 199(1-3):10-26.[16] Lamy-Mendes A , Silva R F , Luisa Dures. Advances in carbon nanostructure-silica aerogel composites: A review[J]. Journal of Materials Chemistry A, 2017, 6(4):1340-1369.[17] Paris J L , Mannaris C , M. Victoria Cabaas, et al. Ultrasound-Mediated Cavitation-Enhanced Extravasation of Mesoporous Silica Nanoparticles for Controlled-Release Drug Delivery[J]. Chemical Engineering Journal, 2017, 340:2-8.[18] 唐祥龙,崔升,张鑫,等.磁性气凝胶的研究进展[J].中国材料进展2016,35(12):937-942.[19] Yang D , Yang G , Yang P , et al. Assembly of Au Plasmonic Photothermal Agent and Iron Oxide Nanoparticles on Ultrathin Black Phosphorus for Targeted Photothermal and Photodynamic Cancer Therapy[J]. Advanced Functional Materials, 2017, 27(18):1700371.[20] Nosrati H , Sefidi N , Sharafi A , et al. Bovine Serum Albumin (BSA) coated iron oxide magnetic nanoparticles as biocompatible carriers for curcumin-anticancer drug[J]. Bioorganic Chemistry, 2018, 76:501-509.[21] Jaeyun Kim Dr, Hoe Suk Kim Dr, Nohyun Lee, et al. Multifunctional Uniform Nanoparticles Composed of a Magnetite Nanocrystal Core and a Mesoporous Silica Shell for Magnetic Resonance and Fluorescence Imaging and for Drug Delivery[J]. Angew Chem Int Ed Engl, 2008, 120(44):8566-8569.[22] Liu X , Tao Y , Mao H , et al. Construction of magnetic-targeted and NIR irradiation- controlled drug delivery platform with Fe3O4@Au@SiO2 nanospheres[J]. Ceramics [23] S.S.Kistler. Coherent expanded aerogels and jellies[J]. Nature, 1931,127:741-742.[24] Alfredo, Snchez, Karina, et al. Hybrid Decorated Core@Shell Janus Nanoparticles as a Flexible Platform for Targeted Multimodal Molecular Bioimaging of Cancer.[J]. ACS Applied Materials Interfaces, 2018,10(37):31032-31043.[25] Hu X, Wang Y, Zhang L, et al. Magnetic field-driven drug release from modified iron oxide-integrated polysaccharide hydrogel[J]. International journal of biological macromolecules, 2018, 108: 558-567.[26] Ha P T, Le T T H, Bui T Q, et al. Doxorubicin release by magnetic inductive heating and in vivo hyperthermia-chemotherapy combined cancer treatment of multifunctional magnetic nanoparticles[J]. New Journal of Chemistry, 2019, 43(14): 5404-5413.
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