1. 毕业设计(论文)的内容和要求
近些年来,具有一定营养价值或药理功能的天然多酚类物质如姜黄素引起了人们的普遍关注。
姜黄素是一种从植物姜根中提取出来的天然黄色脂溶性色素。
姜黄素是中药姜黄的主要成分,由于姜黄素广泛的药学及生物学作用,作为一种有良好发展前景的抗癌药物,姜黄素己经成为研究的焦点并且姜黄素在癌症预防和治疗方面的作用已经引起人们的重视。
2. 参考文献
[1]He Y, Yue Y, Zheng X, et al. Curcumin, Inflammation, andChronicDiseases:How Are They Linked?[J], Molecules. 2015, 20(5): 9183-9213. [2]Loganes C, Lega S, Bramuzzo M, et al. Curcumin Anti-Apoptotic Action in a Model of Intestinal Epithelial Inflammatory Damage[J], Nutrients. 2017, 9(6). [3]Chen X, Zou L Q, Niu J, et al. The Stability, Sustained Release and Cellular Antioxidant Activity of Curcumin Nanoliposomes[J].Molecules.2015,20(8): 14293-14311. [4]Kim E J, Lewis D J, Dabaja B S, et al. Curcumin for the treatment of tumor-stage mycosis fungoides[J], Dermatologic therapy. 2017. [5]Luthra P M, Lal N. Prospective of curcumin, a pleiotropic signalling moleculefrom Curcuma longa in the treatment of Glioblastoma[J], European journal ofmedicinal chemistry.2016,109:23-35. [6]Keihanian F,Saeidinia A,Bagheri RK,et al.Curcumin,hemostasis thrombosis,and coagulation[J].J Cell Physiol,2018,233( 6):4497-4511.[7]Kocaadam B, S, anlier N. Curcumin, an active component of turmeric (Curcuma longa), and its effects on health [J]. Critical Reviews in Food Science and Nutrition, 2017,57(13): 2889-2895.[8]Anand P,Kunnumakkara A B,Newman R A,et al.Bioavailability of curcumin:problems and promises[J].Molecular Pharmaceutics,2007,4:807-818. [9]王春彬,高大中.姜黄素的研究进展以及在心血管疾病中的应用[J].心血管病学进展,2005,26(6):614-616.[10]Tonnesen H H. Solubility, chemical and photochemical stability of curcumin in surfactant solutions. Studies of curcumin and curcuminoids, XXVIII[J], Pharmazie. 2002, 57(12): 820-824. [11]Li J, Lee I W,Shin G H,et al.Curcumin-Eudragit(R) E PO solid dispersion:A simple and potent method to solve the problems of curcumin[J],Eur J Pharm Biopharm.2015,94:322-332. [12]Tong R, Kohane D S. New Strategies in Cancer Nanomedicine[J], Annual review of pharmacology and toxicology. 2016, 56: 41-57. [13]Wang X,Jiang Y,Wang Y W,et al.Enhancing anti-inflammation activity of curcumin through O/W nanoemulsions[J].Food Chemistry.2008,108:419-424.[14]吴雪松.姜黄素脂质体的制备及包封率的测定[J].北方药学,2015,12(5),8-9.[15]Yu H,Huang Q.Enhanced in vitro anti-cancer activity of curcumin encapusulated in hydrophobically modified starch[J].Food Chemistry,2010,119:669-674.[16]Lian T,Ho RJ.Trens and developments in liposome drug delivery systems[J].J Phara Sci,2001,90(6):667-680.[17]Maurer N,Fenske D B,Cullis P R.Development in liposonml drug delivery system[J].Expert Opin Bio Ther,2001,1,(6):923-947.[18]Cartel L,Ceruti M,Dosio F.From conventional to stealth liposomes:a new frontier in cancer chemotherapy[J].Tumor.2003,89(3):237-249.[19]Gabizon A,Shmeeda H,Barenholz Y.Pharmacokinetics of pegylated iilxbomalDoxorubicin:review of anmml and human studies[J].Clin Pharmacokinet.2003,42(5):419-436.[20]Nisini R,Poerio N,Mariotti S,et al.The multirole of liposomes in therapy and prevention of infectious diseases[J].Front Immunol,2018,9:155.[21]Xu H Z,Gong Z,Zhou S Y,et al.Liposomal curcumin targeting endometrial cancer through the NF-κB pathway[J].Cell Physiol Biochem,2018,48(2):569-582.
以上是毕业论文任务书,课题毕业论文、开题报告、外文翻译、程序设计、图纸设计等资料可联系客服协助查找。