诺蒎酮合成含氮杂环有机荧光化合物的研究任务书

 2022-02-21 20:10:26

1. 1. 毕业设计(论文)的内容、要求、设计方案、规划等

β-蒎烯是松节油的主要成分之一,其中,松节油是世界上产量最大的一种天然芳香油,年产约27万吨,中国年产达12万吨之多,居世界首位。诺蒎酮是β-蒎烯的衍生物之一。它具有羰基,反应活性较高,以其为原料合成了多个新的化合物,如对异丙基苯酚,三唑酮类化合物,手性茚类化合物,手性1,3-氨基乙醇和1,3-二醇等,合成药物的研究较多。因此,通过对蒎烯环进行结构修饰,引入功能基团拓展功能,实现其在有机荧光材料方面新的应用,具有重要的现实意义和实用价值。

有机光学材料在电致发光、显示器件及传感器领域等都有着广泛的应用。发光效率是衡量光学材料实用性及性能的重要指标之一,但经典的光学材料在高浓度或固态(如薄膜和晶态)时由于分子间强烈的相互作用,使激发态分子的能量倾向于通过非辐射途径衰减,这就大大降低了材料的固态发光效率,还经常伴随着发射峰的变宽或红移,使光学性能变差。聚集荧光增强分子能够克服普通荧光分子在聚集状态下荧光量子产率下降甚至荧光淬灭的缺点,为有机发光材料在有机发光二极管(OLED)、固体器件中的广泛应用开辟了新的途径。

荧光探针是指由发光基团和特异性反应基团连接而成的新型分子,其与目标物响应前后,可使体系的荧光性质发生某种可检测到的变化,被广泛应用于生物大分子、活性小分子、金属离子、有害气体等的定性和定量检测方面。荧光探针可依据被分析物的物理或化学性质的变化而发生相应的荧光信号变化,所依托的荧光分析法具有设备简单、测试迅速、成本低廉等优点。大多数的有机荧光探针具有合成较简单、荧光量子产率较高、易于进入细胞等优点。

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