1. 毕业设计（论文）的内容和要求
聚谷氨酸是一种氨基酸聚合物，在自然界或人体内能生物降解成内源性物质谷氨酸，不易产生蓄积和毒副作用。
阿霉素 ( doxorubicin) 是一种常用的抗肿瘤药，临床上广泛应用于恶性肿瘤的治疗。
但该药具有较强的心脏毒性及骨髓抑制作用，在一定程度上限制了其临床应用。
2. 参考文献
[1] Feng X, et al. (1997) Functionalized monolayers on ordered mesoporous supports. Science 276(5314):923-926[2] Wu YY, et al. (2004) Composite mesostructures by nano-confinement. (Translated from English) Nat Mater 3(11):816-822.[3] Malenfant PRL, Wan JL, Taylor ST, Manoharan M (2007) Self-assembly of an organic-inorganic block copolymer for nano-ordered ceramics. (Translated from English) Nat Nanotechnol 2(1):43-46.[4] Piao Y, et al. (2008) Wrap-bake-peel process for nanostructural transformation from beta-FeOOH nanorods to biocompatible iron oxide nanocapsules. (Translated from English) Nat Mater 7(3):242-247.[5] Kim JK, Lee E, Lim YB, Lee M (2008) Supramolecular capsules with gated pores from an amphiphilic rod assembly. Angew Chem Int Edit 47(25):4662-4666.[6] Jeong B, Bae YH, Lee DS, Kim SW (1997) Biodegradable block copolymers as injectable drug-delivery systems. Nature 388(6645):860-862.[7] Liu LH, et al. (2009) Self-assembled cationic peptide nanoparticles as an efficient antimicrobial agent. Nat Nanotechnol 4(7):457-463.[8] Ding ZL, Fong RB, Long CJ, Stayton PS, Hoffman AS (2001) Size-dependent control of the binding of biotinylated proteins to streptavidin using a polymer shield. Nature 411(6833):59-62.[9] Nishida K, et al. (2004) Corneal reconstruction with tissue-engineered cell sheets composed of autologous oral mucosal epithelium. New Engl J Med 351(12):1187-1196.[10] Escobar-Chavez JJ, et al. (2006) Applications of thermoreversible pluronic F-127 gels in pharmaceutical formulations. (Translated from English) J Pharm Pharm Sci 9(3):339-358 (in English).[11] Rill RL, Locke BR, Liu YJ, Van Winkle DH (1998) Electrophoresis in lyotropic polymer liquid crystals. (Translated from English) P Natl Acad Sci USA 95(4):1534-1539 (in English).[12] Mortensen K Perdersen S (1993) Structural study on the micelle formation of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) triblock copolymer in aqueous solution. Macromolecules 26:805-812.[13] Deng C, et al. (2006) Synthesis and characterization of RGD peptide grafted poly(ethylene glycol)-b-poly(L-lactide)-b-poly(L-glutamic acid) triblock copolymer. Biomacromolecules 7(2):590-596.[14] Park SY, Lee Y, Bae KH, Ahn CH, Park TG (2007) Temperature/pH-sensitive hydrogels prepared from pluronic copolymers end-capped with carboxylic acid groups via an oligolactide spacer. Macromol Rapid Comm 28(10):1172-1176.[15] Hersel U, Dahmen C, Kessler H (2003) RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials 24(24):4385-4415.[16] Booth C Attwood D (2000) Effects of block architecture and composition on the association properties of poly(oxyalkylene) copolymers in aqueous solution. Macromol Rapid Comm 21(9):501-527.[17] The dye solubilization method is based on the enhanced absorbance of a hydrophobic dye (1,6-diphenyl-1,3,5-hexatriene) at 340, 356, and 378 nm.The absorbance was measured as the temperature increases at a fixed polymer concentration at 0.1 wt.% and dye concentration at 4 mM.Alexandridis P., Holzwarth JF Hatton TA (1994) Micellization of Poly(Ethylene Oxide)-Poly(Propylene Oxide)-Poly(Ethylene Oxide) Triblock Copolymers in Aqueous-Solutions - Thermodynamics of Copolymer Association. Macromolecules 27(9):2414-2425.[18] Joo MK, Park MH, Choi BG, Jeong B (2009) Reverse thermogelling biodegradable polymer aqueous solutions. J Mater Chem 19(33):5891-5905.[19] Xiong XY, Tam KC, Gan LH (2005) Synthesis and thermal responsive properties of P(LA-b-EO-b-PO-b-EO-b-LA) block copolymers with short hydrophobic poly(lactic acid) (PLA) segments. Polymer 46(6):1841-1850.[20] Lam YM, Grigorieff N, Goldbeck-Wood G (1999) Direct visualisation of micelles of Pluronic block copolymers in aqueous solution by cryo-TEM. Phys Chem Chem Phys 1(14):3331-3334.
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