全文总字数：3129字
1. 毕业设计（论文）的内容和要求
水凝胶作为一种极亲水的三维网络结构，其高吸水性以及于软组织类似的结构与性质使得水凝胶材料作为一种软组织替代物被广泛研究。
本研究基于天然高分子材料制备一种生物相容性优异且力学性能良好的可注射水凝胶材料。
2. 实验内容和要求
本课题对学生所学知识和技能的要求： 1、对生物基材料进行仿生化修饰； 2、构建可注射水凝胶支架； 3、对合成水凝胶进行性能表征。
3. 参考文献
(1) Suzuki, T.; Kuramoto, Y.; Kamiya, H. Reduction of Werner Syndrome Protein Enhances G:C --> A:T Transition by O(6)-Methylguanine in Human Cells. Chem Res Toxicol 2018, 31 (5), 319-324, DOI: 10.1021/acs.chemrestox.8b00009.(2) Xu, R.; Luo, G.; Xia, H.; He, W.; Zhao, J.; Liu, B.; Tan, J.; Zhou, J.; Liu, D.; Wang, Y.; Yao, Z.; Zhan, R.; Yang, S.; Wu, J. Novel bilayer wound dressing composed of silicone rubber with particular micropores enhanced wound re-epithelialization and contraction. Biomaterials 2015, 40, 1-11, DOI: 10.1016/j.biomaterials.2014.10.077.(3) Feng, Z.; Su, Q.; Zhang, C.; Huang, P.; Song, H.; Dong, A.; Kong, D.; Wang, W. Bioinspired Nanofibrous Glycopeptide Hydrogel Dressing for Accelerating Wound Healing: A Cytokine‐Free, M2‐Type Macrophage Polarization Approach. Advanced Functional Materials 2020, DOI: 10.1002/adfm.202006454.(4) Blacklow, S. O.; Li, J.; Freedman, B.; Zeidi, M.; Mooney, D. J. J. e. A. Bioinspired mechanically active adhesive dressings to accelerate wound closure. 2019, 5 (7), eaaw3963.(5) Liang, Y.; Zhao, X.; Hu, T.; Han, Y.; Guo, B. Mussel-inspired, antibacterial, conductive, antioxidant, injectable composite hydrogel wound dressing to promote the regeneration of infected skin. J Colloid Interface Sci 2019, 556, 514-528, DOI: 10.1016/j.jcis.2019.08.083.(6) Chen, W.; Shen, X.; Hu, Y.; Xu, K.; Ran, Q.; Yu, Y.; Dai, L.; Yuan, Z.; Huang, L.; Shen, T.; Cai, K. Surface functionalization of titanium implants with chitosan-catechol conjugate for suppression of ROS-induced cells damage and improvement of osteogenesis. Biomaterials 2017, 114, 82-96, DOI: 10.1016/j.biomaterials.2016.10.055.(7) Dunnill, C.; Patton, T.; Brennan, J.; Barrett, J.; Dryden, M.; Cooke, J.; Leaper, D.; Georgopoulos, N. T. Reactive oxygen species (ROS) and wound healing: the functional role of ROS and emerging ROS-modulating technologies for augmentation of the healing process. International Wound Journal 2017, 14 (1), 89-96, DOI: 10.1111/iwj.12557.(8) Zhao, X.; Wu, H.; Guo, B.; Dong, R.; Qiu, Y.; Ma, P. X. Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing. Biomaterials 2017, 122, 34-47, DOI: 10.1016/j.biomaterials.2017.01.011.(9) Chen, W.; Zhu, Y.; Zhang, Z.; Gao, Y.; Liu, W.; Borjihan, Q.; Qu, H.; Zhang, Y.; Zhang, Y.; Wang, Y.-J.; Zhang, L.; Dong, A. Engineering a multifunctional N-halamine-based antibacterial hydrogel using a super-convenient strategy for infected skin defect therapy. Chemical Engineering Journal 2020, 379, DOI: 10.1016/j.cej.2019.122238.(10) Zhang, Y. S.; Khademhosseini, A. Advances in engineering hydrogels. Science 2017, 356 (6337), DOI: 10.1126/science.aaf3627.
4. 毕业设计（论文）计划
2021.1.21前：查阅文献，做好前期工作。
2021.2.21前：完成外文翻译、文献综述和开题报告。
2021.5.3前：进行课题实验、设计、实验结果的处理和分析、准备中期检查。
以上是毕业论文任务书，课题毕业论文、开题报告、外文翻译、程序设计、图纸设计等资料可联系客服协助查找。
