全文总字数：3214字
1. 毕业设计（论文）的内容和要求
1、毕业论文内容生物表面活性剂槐糖脂 (Sophorolipids) 通常由一分子槐糖（两分子的葡萄糖通过β-1,2糖苷键结合）与饱和度不同、碳链长度为16/18的β-脂肪酸组成。
它通常是由非致病性酵母菌株产生的一系列具有相似分子结构的次级代谢产物，具有低毒、可生物降解、生态安全和良好的乳化、分散、增溶等特点，在医药[1]、食品[2]、日化[3]、环境保护[4]等领域具有很大的潜在应用价值[5]。
槐糖脂主要可以分为两种：内酯型和酸型[5]。
2. 实验内容和要求
1、实验内容1) 槐糖脂的提纯。
2) 酶催化反应的设计及优化。
3) 改造后的脱乙酰内酯型槐糖脂结构的鉴定分析（液相色谱、液相质谱）。
3. 参考文献
1. Sajid M, Khan MSA, Cameotra SS, Al-Thubiani AS: Biosurfactants: Potential applications as immunomodulator drugs. Immunology Letters 2020, 223:71-77.2. Ribeiro BG, Guerra JMC, Sarubbo LA: Biosurfactants: Production and application prospects in the food industry. Biotechnology Progress 2020, 36:16.3. Morya VK, Ahn C, Jeon S, Kim EK: Medicinal and Cosmetic Potentials of Sophorolipids. Mini-Reviews In Medicinal Chemistry 2013, 13:1761-1768.4. Patel S, Homaei A, Patil S, Daverey A: Microbial biosurfactants for oil spill remediation: pitfalls and potentials. Applied Microbiology And Biotechnology 2019, 103:27-37.5. Li Y, Chen Y, Tian X, Chu J: Advances in sophorolipid-producing strain performance improvement and fermentation optimization technology. Applied Microbiology And Biotechnology 2020.6. Shah V, Doncel GF, Seyoum T, Eaton KM, Zalenskaya I, Hagver R, Azim A, Gross R: Sophorolipids, microbial glycolipids with anti-human immunodeficiency virus and sperm-immobilizing activities. Antimicrobial Agents And Chemotherapy 2005, 49:4093-4100.7. Chen J, Liu R, Liu Y, Liu X: Inhibition of K562 cancer cells by lactonic diacetyl-sophorolipid. Chinese Journal of Applied Environmental Biology 2015, 21:377-380.8. Wang HM, Roelants S, To MH, Patria RD, Kaur G, Lau NS, Lau CY, Van Bogaert INA, Soetaert W, Lin CSK: Starmerella bombicola: recent advances on sophorolipid production and prospects of waste stream utilization. Journal Of Chemical Technology And Biotechnology 2019, 94:999-1007.9. Ma X-J, Li H, Shao L-J, Shen J, Song X: Effects of nitrogen sources on production and composition of sophorolipids by Wickerhamiella domercqiae var. sophorolipid CGMCC 1576. Applied Microbiology And Biotechnology 2011, 91:1623-1632.10. 潘洪哲, 包木太, 林军章, 刘涛, 宋永亭, 李希明: 内酯型槐糖脂生物表面活性剂性能评价. 油气地质与采收率 2013:88-91 120-121.
4. 毕业设计（论文）计划
12.30~1.15文献查阅及资料研读1.16~2.25 确定实验方案及开题报告写作2.26~3.30 脱乙酰内酯型槐糖脂的制备及纯化鉴定3.31~5.15 脱乙酰内酯型槐糖脂在MEOR中的应用评价5.16~5.31 毕业论文撰写
以上是毕业论文任务书，课题毕业论文、开题报告、外文翻译、程序设计、图纸设计等资料可联系客服协助查找。
