1. 毕业设计（论文）的内容和要求
恙虫病是通过恙螨叮咬人而传播的虫媒传染病，在我国几乎所有的省市都有发病的报告，疫区呈不断扩大态势,已成为我国不容忽视的公共卫生问题。
由于该病临床症状与许多热性病相似，易误诊，而且常规抗生素治疗无效，极易延误病情，甚至出现死亡病例。
因此，快速、准确的诊断非常重要。
2. 参考文献
1.Lu HY, Tsai KH, Yu SK, et al. Phylogenetic analysis of 56-kDa type-specific antigen gene of Orientia tsutsugamushi isolates in Taiwan. Am J Trop Med Hyg.2010 Sep;83(3):658-63.2. 操敏，王忠灿，陆年红，黄华东，郭恒彬，王长军，张兴，唐家琪.安徽三界地区啮齿动物感染恙虫病东方体调查.中国人兽共患病学报2011，27（8）:77-803.Stover ck, Marana DP, Carter JM, et al The 56-Kilodalton major Protein antigen of Rickettsia tsutsugamushi :Molecular cloning and sequence analysis of sta 56 gene and precise identification of a strain-specific epitope. J Infect Immun , 1990, 58:2076-20844.Daryl J. Kelly,Paul A. Fuerst,Wei-Mei Ching, et al.Scrub Typhus: The geographic distribution of phenotypic and genotypic variants of Orientia tsutsugamushi.Clinical Infectious Diseases, 2009, 48:2032305.Sang-Won Park , Chi Kug Lee , Yee Gyung Kwak , et al. Antigenic Drift of Orientia tsutsugamushi in South Korea as Identified by the Sequence Analysis of a 56-kDa Protein-Encoding Gene. Am. J. Trop. Med. Hyg., 83(4), 2010, 9309356．操敏，郭恒彬 恙虫病东方体感染的实验室诊断技术研究进展【J】国外医学临床生物化学与检验学分册，2003，24（2）：76-77，867.Min Cao,Hengbin Guo,Tang Tang,et al.Preparation of Recombinant Antigen of Tsutsugamushi Ptan Strain and Development of Rapid Diagnostic Reagent for Scrub Typhus. Am J Trop Med Hyg,2007,76（3）：553-5588.Min Cao, Li Che, Jinhai Zhang, Determination of Scrub typhus Suggests a New Epidemic Focus in the Anhui Province of China.scientific reports.2016.2
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