1. 毕业设计(论文)的内容和要求
一氧化碳(CO)是近几十年来经研究证实具有重要的生物信号传递分子之一,在生物体内它可以与氧气竞争性结合血红蛋白,从而阻碍氧气的正常运输。
如果 过量摄入外源性的一氧化碳可导致生物机体中一氧化碳中毒,因此一氧化碳曾长 期被认为仅仅是一种有毒有害的物质,而体内是否真实的存在内源性一氧化碳, 以及内源性一氧化碳是否具有生理作用却长期被人们所忽视。
因此发展用于生物样品中对生物活性分子一氧化碳有高灵敏、快速而又有高选择性的检测技术和方法,尤其是在复杂介质环境中对一氧化碳能高选择性识别和测定的方法,具有非常重要的生物学意义。
2. 参考文献
[1] 贾美琳,陈庆,蒋宛莉,谷威,王筱梅. 喹啉盐与吡啶盐花青染料分子酸致变色行为的研[J].信息记录材料.2009(05).[2]刘晁清,王玲玲,肖经纬,宋国梁,刘浩.Er3 掺杂的氧化钇纳米上转化发光性质的研究[J].材料导报.2006,11(20):47-49.[3]李雅丽,孟燕.几种花青染料的合成及分离[J].西安工程学院学报.1999,09(21):91-93.[4] Wang C, Cheng L, Liu Y, Wang X, Ma X, Deng Z, et al. Imaging-guided pHsensitive photodynamic therapy using charge reversible upconversion nanoparticles under near-infrared light. Adv Funct Mater 2013;23:3077-86.[5] Cheng L, Yang K, Li Y, Chen J, Wang C, Shao M, et al. Facile preparation of multifunctional upconversion nanoprobes for multimodal imaging and dualtargeted photothermal therapy. Angew Chem Int Ed 2011;50:7385-90.[6] Zhang C, Zhou H-P, Liao L-Y, Feng W, Sun W, Li Z-X, et al. Luminescence modulation of ordered upconversion nanopatterns by a photochromic diarylethene: rewritable optical storage with nondestructive readout. Adv Mater 2010;22:633-7.[7] Feng W, Han C, Li F. Upconversion-nanophosphor-based functional nanocomposites. Adv Mater 2013;25:5287-303.[8]Chunwei Yu,Ying Wang,Ke Xu.Characterization of a highly Cu2 -selective fluorescent probe derived from rhodamine B[J].Dyes Pigm,2013,96,38.[9]J Pan,P Zhan,M Hu.A fluorescent rationmetric chemodosimeter for Cu2 based on TBET and its application in living cells[J].Org Lett.,2013,15,492[10]M Kumar,N Kumar,V.Bhalla.Highly selective fluorescence turn-on chemodosimeter based on rhodamine for nanomolar detection of copper ions[J].Org Lett.,2012,14,406[11]J Liu,C Li,F Li.Fluorescence turn-on chemodosimeter-functionalized mesoporous silca nano- particles and their application in cell imaging[J].J.Mater.Chem.,2011,21,7175.[12]Puhui Xie,Fengqi Guo,Dan Li.A Cu2 chemodosimeter based on amplified fluorescence in the red region[J].J.Lumin.,2011,131,104.[13]D Wang,Y Shiraishi,T Hirai.A BODIPY-based fluorescent chemodosimeter for Cu(II) driven by an oxidative dehydrogenation mechanism[J].Chem,Commun.,2011,47,2673.[14] Fenton, H H. On a new reaction of tartaric acid [J]. Chem. News., 1876, 33, 190.[15] Benesi H A, Hildebrand J H. A spectrophotometric investigation of the interaction of iodine with aromatic hydrocarbons [J]. J. Am. Chem. Soc., 1949, 71(8): 2703-2707.[16] Yang Y K, Ko S K, Shin I, et al. Synthesis of a highly metal-selective rhodaminebased probe and its use for the in vivo monitoring of mercury [J]. Nature Protocols. 2007, 2(7): 1740-1745.[17] Taki M, Iyoshi S, Ojida A, et al. Development of highly sensitive fluorescent probes for detection of intracellular copper(I) in living systems [J]. J. Am. Chem. Soc., 2010, 132(17): 5938-5939. [18] Chen X, Ko S K, Kim M J, et al. A thiol-specific fluorescent probe and its application for bioimaging [J]. Chem. Commun., 2010, 46(16): 2751-2753.
以上是毕业论文任务书,课题毕业论文、开题报告、外文翻译、程序设计、图纸设计等资料可联系客服协助查找。