1. 毕业设计（论文）的内容和要求
1．文献查阅
掌握文献查阅的一般方法，学会使用计算机在中国期刊网，维普数据库，超星数字图书馆，美国化学学会（ACS）数据库，CA，SCI等检索资源上查阅关于铜催化无溶剂条件下三组分反应合成炔丙胺的相关文献。
2．文献阅读及综述
2. 参考文献
[1] (a) Huffman MA, Yasuda N, DeCamp AE, Grabowski EJJ. Lithium alkoxides of cinchona alkaloids as chiral controllers for enantioselective acetylide addition to cyclic N-acyl ketimines [J]. J. Org. Chem, 1995, 60: 1590. (b) Enders D, Reinhold U. Asymmetric synthesis of amines by nucleophilic 1, 2-addition of organometallic reagents to the CN-double bond [J]. Tetrahedron: Asymmetry, 1997, 8: 1895. (c) Kauffman GS, Harris GD, Dorow RL, Stone BRP,Parsons, RLJ, Pesti JA, Magnus NA, Fortunak JM, Confalone PN, Nugent WA. An Efficient Chiral Moderator Prepared from Inexpensive ( )-3-Carene: Synthesis of the HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor DPC 963 [J]. Org. Lett, 2000, 2: 3119.
[2] (a) Magueur G, Crousse B, Bonnet-Delpon D. Direct access to CF3-propargyl amines and conversion to difluoromethyl imines [J].Tetrahedron Lett, 2005, 46: 22192221; (b) Ma Y, Lobkovsky E, Collum DB. BF3-Mediated Additions of Organolithiums to Ketimines: X-ray Crystal Structures of BF3-Ketimine Complexes [J]. J. Org. Chem, 2005, 70: 23352337; (c) Aubrecht KB, Winemiller MD, Callum DB. BF3-Mediated Addition of Lithium Phenylacetylide to an Imine: Correlations of Structures and Reactivities. BF3⊙ R3N Derivatives as Substitutes for BF3⊙ Et2O [J]. J. Am. Chem. Soc, 2000, 122: 1108411089.
[3] (a) Brannock KC, Burpitt RD, Thweatt JG. Enamine Chemistry. I. Reactions with Nonactivated Terminal Acetylenic Compounds1 [J]. J. Org.Chem, 1963, 28: 14621464; (b) Fischer C, Carreira EM. Direct addition of TMS-acetylene to aldimines catalyzed by a simple, commercially available Ir (I) complex [J]. Org. Lett, 2001, 3: 43194321; (c) Benaglia M, Negri D, DellAnna G. Enantioselective addition of phenyl and alkyl acetylenes to imines catalyzed by chiral Cu (I) complexes [J]. Tetrahedron Lett, 2004, 45: 87058708; (d) Colombo F, Benaglia M, Orlandi S, Usuelli F, Celentano G. Very mild, enantioselective synthesis of propargylamines catalyzed by copper (I)-bisimine complexes [J]. J. Org. Chem., 2006, 71: 20642070.
以上是毕业论文任务书，课题毕业论文、开题报告、外文翻译、程序设计、图纸设计等资料可联系客服协助查找。
