1. 毕业设计（论文）的内容和要求
一、论文内容：1,5-戊二胺是一种具有多种活性的天然多胺， 广泛存在于原核生物和真核生物中，在生物体中由L-赖氨酸经赖氨酸脱羧酶直接脱羧生成。
1,5-戊二胺在保护细胞免受低pH环境中H 的伤害，维持菌体在酸性环境等方面起着重要作用。
近年来，利用生物来源的 1,5-戊二胺替代石油化工来源的己二胺合成生物基聚酰胺的研究也逐步展开。
2. 参考文献
[1] Kloss, R., M.H. Limberg and U. Mackfeld, et al., Catalytically active inclusion bodies of L-lysine decarboxylase from E. coli for 1,5-diaminopentane production. SCIENTIFIC REPORTS, 2018. 8: 136-147.[2] Jia, H., H. Wang and K. Ma, et al., Effect of thermodynamic parameters on prediction of phase behavior and process design of extractive distillation. CHINESE JOURNAL OF CHEMICAL ENGINEERING, 2018. 26(5): 993-1002.[3] Cheng, C., F.N. Mutua and Y. Dong, et al., Bio-based poly(pentamethylene oxamide) synthesized by spray/solid-state polycondensation. POLYMER BULLETIN, 2018. 75(1): 121-134.[4] Jancewicz, A.L., N.M. Gibbs and P.H. Masson, Cadaverine's Functional Role in Plant Development and Environmental Response. FRONTIERS IN PLANT SCIENCE, 2016. 7: 1-8.[5] Bhatia, S.K., R.K. Bhatia and Y.-H. Yang, Biosynthesis of polyesters and polyamide building blocks using microbial fermentation and biotransformation. REVIEWS IN ENVIRONMENTAL SCIENCE AND BIO-TECHNOLOGY, 2016. 15(4): 639-663.[6] Oh, Y.H., K.-H. Kang and M.J. Kwon, et al., Development of engineered Escherichia coli whole-cell biocatalysts for high-level conversion of L-lysine into cadaverine. JOURNAL OF INDUSTRIAL MICROBIOLOGY BIOTECHNOLOGY, 2015. 42(11): 1481-1491.[7] Lessmeier, L., J. Pfeifenschneider and M. Carnicer, et al., Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2015. 99(23): 10163-10176.[8] Furukawa, H., F. Gandara and Y.-B. Zhang, et al., Water Adsorption in Porous Metal-Organic Frameworks and Related Materials. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014. 136(11): 4369-4381.[9] Gil, I.D., D.C. Botia and P. Ortiz, et al., Extractive Distillation of Acetone/Methanol Mixture Using Water as Entrainer. INDUSTRIAL ENGINEERING CHEMISTRY RESEARCH, 2009. 48(10): 4858-4865.[10] Liang, H.J., H. Gao and Q.Q. Kong, et al., Adsorption equilibrium and kinetics of tetrahydrofuran plus water solution mixture on zeolite 4A. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 2006. 51(1): 119-122.[11] Dantan, N., W. Frenzel and S. Kuppers, Determination of water traces in various organic solvents using Karl Fischer method under FIA conditions. TALANTA, 2000. 52(1): 101-109.
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