1. 毕业设计(论文)的内容和要求
2-芳基苯并硒唑类化合物作为结构单元在新材料、有机中间体、活性分子合成中具有广泛的应用。
常用的制备方法包括2-氨基苯酚在较高温度或氧化剂存在下与醛、酸、苄醇或苄胺缩合反应等。
常用的制备方法包括双(二氨基苯基)二硒化合物在氧化剂存在下与醛、酸、α-酮酸等缩合反应;Se-催化下2-碘苯胺与醛、芳甲基氯、芳基乙酸等在过渡金属催化或氧化条件制备等。
2. 参考文献
1.Xin Wang; Dazhuang Miao; Xiaotong Li; Renhe Hu; Zhao Yang; Ren Gu; Shiqing Han,Elemental sulfur mediated cyclization via redox strategy: Synthesis of benzothiazoles from o-chloronitrobenzenes and benzyl chlorides. Tetrahedron 2017, 73, 5194-5199.2. Le Anh Nguyen; Quoc Anh Ngo; Pascal Retailleau and Thanh Binh Nguyen, Elemental sulfur as a polyvalent reagent in redox condensation with o-chloronitrobenzenes and benzaldehydes: three-component access to 2-arylbenzothiazoles. Green Chemistry 2017, 19, 4289.3. Ren Gu; Xin Wang; Zhao Yang; Shiqing Han, Se-mediated one-pot synthesis of 2-substituted benzoselenazole derivatives from 2 to iodoanilines and arylacetic acids/arylmethyl chlorides. Tetrahedron Letters 2018, 59, 2835-2838.4. Zhou meiyun; Wu zhaojun; Li yiqun; Zheng wenjie; Ji shengbin; Zhou hua,One-Pot Synthesis of Benzo[d][1,3]selenazole Derivatives by Using Carbon-Supported Copper Catalyst. Chin. J. Org. Chem. 2015, 35, 1270-1275.5.Haifeng Gan; Douglas R. Macfarlane, Facile preparation of 2-arylbenzoselenazoles from three components reactions: 2-Chloronitrobenzene, Se, and arylacetic acids. Tetrahedron Letters, 2019, 61,151393. 6. Haifeng Gan, Facile Preparation of Benzoxazoles from S8-Promoted Cyclization of 2-Nitrophenols with Arylmethyl Chloride. ChemistrySelect 2019, 4, 2858-2860.7. Haifeng Gan; Dazhuang Miao; Qiang Pan; Renhe Hu; Xiaotong Li; Shiqing Han, S8 -Mediated Cyclization of 2-Aminophenols/thiophenols with Arylmethyl Chloride: Approach to Benzoxazoles and Benzothiazoles. Chem. Asian J. 2016, 11, 1770-1774.8. Tao Su; Shishun Xie; Bifu Li; Jun Yan; Ling Huang; Xingshu Li, Copper-Catalyzed Three-Component One-Pot Synthesis of Substituted 2-Aryl-1,3-benzoselenazoles. Synlett 2015, 26, 215220.9. Haifeng Gan, Iron/S8 -Catalyzed Redox Condensation of o-Nitroarenes with Arylmethyl Chloride: Synthesis of Benzimidazoles and Benzothiazoles. Asian J. Org. Chem. 2016, 5, 1111-1114.
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