全文总字数:3580字
1. 毕业设计(论文)的内容和要求
1、 找到检测月桂酸、月桂酸二酯、月桂酸三酯的分析方法2、 完成对所建立的分析方法的评价要求:建立分析月桂酸、月桂酸二酯、月桂酸三酯的标准曲线;得到上述方法的检测范围、方差、回收率等相关数据。
2. 实验内容和要求
1、 月桂酸、月桂酸二酯、月桂酸三酯的GC方法的建立要求:建立月桂酸、月桂酸二酯、月桂酸三酯的GC方法的标准曲线2、 月桂酸、月桂酸二酯、月桂酸三酯的HPLC方法的建立要求:建立月桂酸、月桂酸二酯、月桂酸三酯的HPLC方法的标准曲线3、 分析上述方法的灵敏度、检测限、精确度等要求:得到上述方法的检测范围、方差、回收率等相关数据。
3. 参考文献
1. Kelly P. Coleman; Jr., W. A. T., Esters of Mono- and Alkenyl Carboxylic Acids and Mono- and Polyalcohols. In Patty's Toxicology, 2012; pp 55-146.2. Jouin, P.; Castro, B.; Zeggaf, C.; Pantaloni, A.; Senet, J. P.; Lecolier, S.; Sennyey, G., MONO-ESTERIFICATION OF N-PROTECTED DI-ACIDS ASPARTIC AND GLUTAMIC BY CHLOROFORMATE ACTIVATION. Tetrahedron Letters 1987, 28 (15), 1665-1668.3. Rytczak, P.; Koziokiewicz, M.; Okruszek, A., The chemical synthesis of phosphorothioate and phosphorodithioate analogues of lysophosphatidic acid (LPA) and cyclic phosphatidic acid (CPA). New J. Chem. 2010, 34 (5), 1008-1017.4. Zhao, M.-j.; Cai, H.-y.; Liu, M.-y.; Deng, L.-l.; Li, Y.; Zhang, H.; Feng, F.-q., Effects of dietary glycerol monolaurate on productive performance, egg quality, serum biochemical indices, and intestinal morphology of laying hens. Journal of Zhejiang University-SCIENCE B 2019, 20 (11), 877-890.5. Glycerol Monolaurate Market 2019 Industry Demand, Share, Global Trend, Industry News, Business Growth, Top Key Players Update, Business Statistics and Research Methodology by Forecast to 2025.6. Lieberman, S.; Enig, M. G.; Preuss, P. H. G., A Review of Monolaurin and Lauric Acid: Natural Virucidal and Bactericidal Agents. Alternative and Complementary Therapies 2006, 12 (6), 310-314.7. Ponphaiboon, J.; Limmatvapirat, S.; Chaidedgumjorn, A.; Limmatvapirat, C., Optimization and comparison of GC-FID and HPLC-ELSD methods for determination of lauric acid, mono-, di-, and trilaurins in modified coconut oil. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences 2018, 1099, 110-116.8. Nakamura, R.; Komura, K.; Sugi, Y., The esterification of glycerine with lauric acid catalyzed by multi-valent metal salts. Selective formation of mono- and dilaurins. Catalysis Communications 2008, 9 (4), 511-515.9. Cubides-Roman, D. C.; Perez, V. H.; de Castro, H. F.; Orrego, C. E.; Giraldo, O. H.; Silveira, E. G.; David, G. F., Ethyl esters (biodiesel) production by Pseudomonas fluorescens lipase immobilized on chitosan with magnetic properties in a bioreactor assisted by electromagnetic field. Fuel 2017, 196, 481-487.10. da Silva, W. F.; Kochepka, D. M.; Dill, L. P.; Wypych, F.; Cordeiro, C. S., Selective synthesis of monolaurin catalyzed by layered zinc laurate. Reaction Kinetics Mechanisms and Catalysis 2019, 128 (2), 779-791.11. Freitas, L.; Santos, J. C.; Barcza, M. V.; de Castro, H. F., POTENTIAL ALTERNATIVE FOR USING THE GLYCEROL GENERATED IN THE BIODIESEL PRODUCTION: ENZYMATIC SYNTHESIS OF MONOLAURIN BY ESTERIFICATION. Quimica Nova 2009, 32 (9), 2277-2281.12. Zhong, N. J.; Gui, Z. Y.; Xu, L.; Huang, J. R.; Hu, K.; Gao, Y. Q.; Zhang, X.; Xu, Z. B.; Su, J. Y.; Li, B., Solvent-free enzymatic synthesis of 1, 3-Diacylglycerols by direct esterification of glycerol with saturated fatty acids. Lipids in Health and Disease 2013, 12.13. Chen, F. L.; Zhang, G. J.; Liu, C. Y.; Zhang, J. Y.; Zhao, F. F.; Xu, B. C., Highly Selective Synthesis of Monolaurin via Enzymatic Transesterification under Batch and Continuous Flow Conditions. J. Oleo Sci. 2019, 68 (11), 1125-1132.
4. 毕业设计(论文)计划
1、1-3周 GC方法的建立和标准曲线的制作2、4-6周 HPLC方法的建立和标准曲线的制作3、9周 方法的验证和评价4、10-13周 数据处理、写论文
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