1. 毕业设计（论文）主要目标：
1.熟悉小动物CT实验所需的实验仪器。
2.学习活体小动物CT门控装置的使用方法。
3.在导师的帮助下获得实验数据，并对数据进行分析。
2. 毕业设计（论文）主要内容：
1.活体小动物CT 的研究背景和制作原理。
2.小动物CT 呼吸门控方案设计。
3.内在回顾性呼吸门控技术开发。
3. 主要参考文献
[1] 李冬梅万春丽李继承小动物活体成像技术研究进展[J] 中国生物医学工程学报2009 28 卷6 期[2]Weiss leder R , P ittet M J . Imaging in the era of molecular oncology[J ] . Nature , 2008 , 452(7187) :580 - 589.
[3]Soenke H. Bartling et.al Small Animal Computed Tomography Imaging Current MedicalImaging Reviews, 2007, 3, 45-59[4]叶乃力用于活体小鼠的微型CT 呼吸门控技术研究[硕士学位论文] 武汉市华中科技大学2012[5]Soenke H. Bartling, Jan Kuntz, Wolfhard Semmler Gating in small-animal cardio-thoracic CTDepartment of Medical Physics in Radiology, German Cancer Research Center (DKFZ)[6]N. L. Ford, et.al In vivo characterization of lung morphology and function in anesthetizedfree-breathing mice using micro-computed tomography[J] Appl Physiol102: 2046 –2055, 2007.[7]Nancy L. Ford et.al Prospective respiratory-gated micro-CT of free breathing rodents 2005American Association of Physicists in Medicine.DOI: 10.1118/1.2013007[8]Feldkamp,L.A.et al.(1984) Practical cone-beam algorithm[J]. J.Opt.Soc.Am.Al,612-619[9]Laurel M Burk et.al Non-contact respiration monitoring for in-vivo murine micro computedtomography: characterization and imaging applications Phys. Med. Biol.57(2012) 5749–5763[10]罗广文红外摄像呼吸监测系统设计与研制[硕士学位论文] 北京清华大学2008[11]Philippe Giraud.et.al Reduction of organ motion in lung tumors with respiratory gating LungCancer (2006)51, 41—51[12]Erin B Walters.et.al Improved method of in vivo respiratory-gated micro-CT imaging Phys.Med. Biol.49(2004) 4163–4172[13]Soenke H. Bartling.et.al Retrospective Motion Gating in Small Animal CT of Mice and RatsInvest Radiol2007;42: 704 –714[14]C Chavarr′as et.al Extraction of the respiratory signal from small-animal CT projections fora retrospective gating method Phys. Med. Biol.53(2008) 4683–4695[15]Soenke H. Bartling et.al Intrinsic respiratory gating in small-animal CT Eur Radiol (2008) 18:1375–1384[16]Wolfgang Recheis Methods of in-vivo mouse lung micro-CT Medical Imaging 2005[17]Jicun Hu et.al Post Acquisition Small Animal Respiratory Gated Imaging Using microCone-Beam CT Medical Imaging 2004[18]仲爱军,龚辉,骆清铭适于小动物研究的微型CT 系统的研制Chinese Journal of MedicalInstrumentation 2004 年第28 卷第5 期[19]仲爱军用于小动物研究的微型CT 系统研制[硕士学位论文]武汉市华中科技大学2004东南大学本科生毕业设计（论文）33[20]田丰,郭晓莲,胡广书适用于微型CT 系统活体成像的新型门控技术航天医学与医学工程2010 年第23 卷第6 期[21]崔友军应用单片机改进螺旋CT 呼吸门控装置现代仪器与医2013 年第19 卷第3 期[22]Robert A. McLaughlin et.al Respiratory gating of anatomical optical coherence tomographyimages of the human airway Optical coherence tomography; (170.2150)[23]J. J. Vaquero et.al Assessment of a New High-Performance Small-Animal X-Ray TomographIEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 55, NO. 3, JUNE 2008[24]Shannon P HOLMES et.al Delineation of an Acquisition Window within the RespiratoryCycle of Laboratory Animals Proc. Intl. Soc. Mag. Reson. Med 9 (2001)[25]Guohua Cao et.al Prospective-gated cardiac micro-CT imaging of free-breathing miceusing carbon nanotube field emission x-ray Med. Phys. 3710…, October 2010
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